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Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Iain Cheeseman and colleagues reveal the underappreciated role of single genes producing multiple proteins in atypical presentations of rare disease, and present case studies of affected patients through a collaboration with Boston Children's Hospital.

7 Nov 2025

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

Intravenous immunoglobulin (IVIG) therapy involves infusing patients with naturally occurring IgG antibodies to treat autoimmune conditions.

7 Nov 2025

New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression

Researchers have unveiled the intricate molecular mechanisms governing TCF/LEF-mediated transcription in the canonical Wnt pathway, identifying these proteins as promising therapeutic targets for cancer and fibrotic diseases.

7 Nov 2025

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

Glycans are important complex carbohydrates found on cell surfaces that serve crucial roles in cell-to-cell communication, structure, and protection.

7 Nov 2025

New method promises to alleviate the symptoms of multiple sclerosis

About 1 million people in the U.S. live with multiple sclerosis, a chronic autoimmune disease that inflames the nervous system and scrambles communication between the brain and body.

7 Nov 2025

Scientists uncover mechanism driving efficient protein deacetylation by Sir2 enzyme

Sir2, an enzyme belonging to sirtuins, has been effectively involved in the deacetylation of proteins. A tandem allosteric effect of reactant and product is responsible for the efficient deacetylation cycle of the Sir2 enzyme, reveal researchers from Science Tokyo.

7 Nov 2025

Exploring endogenous retroviruses as hidden drivers of alcohol use disorder

Alcohol use disorder (AUD), characterized by uncontrollable alcohol consumption due to physical and psychological dependence, affects approximately 14.1 million people in the U.S.

7 Nov 2025

Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer

Cervical squamous cell carcinoma (CESC), the most prevalent subtype of cervical cancer, remains a major global health burden driven primarily by persistent high-risk HPV infection and genetic susceptibility.

7 Nov 2025

Nurses promote hope behind bars in Norwegian prisons

Nurses hold a key position in health and care work in Norwegian prisons. What is it like for them to promote health behind bars? A professor at the University of Agder has written a book about this.

7 Nov 2025

Study reveals trends and future projections of cancer mortality in China

Cancer remains the second leading cause of death in China, accounting for nearly one-quarter of all deaths nationwide. Rapid socioeconomic change, environmental exposure, and an aging population have intensified the burden of cancer across the country.

7 Nov 2025

Study highlights growing mental health concerns among U.S. international student population

Despite international students in U.S. higher education facing significant mental health challenges, national patterns of anxiety, depression, suicidal ideation, and mental health service use among this group remain poorly understood.

7 Nov 2025

Mapping the brain's body regulation and sensing system using 7 Tesla MRI

Jiahe Zhang, PhD, of the Department of Psychiatry at Mass General Brigham, is the lead author of the paper published in Nature Neuroscience, "Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI."

7 Nov 2025

Genomic mapping of resistance mutations in A. baumannii

The bacteria Acinetobacter baumannii (A. baumannii) is a haunting presence in many hospitals in the United States, where more than one in 100 patients are treated for A. baumannii infections.

7 Nov 2025

Radiometer featured in the 2025 edition of the Healthcare & Life Sciences Review Denmark

Radiometer is featured in the 2025 Healthcare & Life Sciences Review, highlighting its role in acute care diagnostics and commitment to patient-centered care.

From Radiometer Medical 7 Nov 2025

Comprehensive kinase atlas reveals new insights into cell signaling and disease

The enzyme RNA polymerase II transcribes genes into messenger RNA. This process is guided by modifications to the enzyme's "tail" called phosphorylation patterns.

7 Nov 2025

Diabetes drug blunts exercise-induced health improvements

A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

7 Nov 2025

Study reveals uneven access to abortion pill mifepristone in British Columbia

Most pharmacies in British Columbia can provide the abortion pill mifepristone within days, but uneven access still leaves some women facing barriers to this time-sensitive medication, according to new research.

7 Nov 2025

New initiative focuses on advancing human disease research through AI and frontier biology

Mark Zuckerberg and Priscilla Chan today announced the launch of a first-of-its-kind initiative combining frontier artificial intelligence and frontier biology to dramatically accelerate scientific progress toward understanding and addressing human disease.

7 Nov 2025

Machine learning advances human-centric drug toxicity prediction

In the UK, there was a case where TGN1412, an immunotherapy under development, triggered a cytokine storm within hours of administration to humans, leading to multiple organ failure.

7 Nov 2025

New project aims to reduce addiction through prevention infrastructure development

Researchers at Wayne State University will work with Michigan agencies and education partners to improve access to school-based substance use prevention and treatment programs for adolescents who are at risk of substance misuse and substance use disorders (SUDs).

7 Nov 2025

Medical News

Multiple protein forms from a single gene offer fresh insight into rare disease mechanisms

Rockefeller scientists engineer next-generation antibody to replace IVIG therapy

New insights reveal how TCF and LEF proteins control Wnt signaling and disease progression

Study reveals structural and cellular clues behind cancer-linked GnT-V enzyme selectivity

New method promises to alleviate the symptoms of multiple sclerosis

Scientists uncover mechanism driving efficient protein deacetylation by Sir2 enzyme

Exploring endogenous retroviruses as hidden drivers of alcohol use disorder

Single-cell analysis reveals HPV-induced keratinocyte heterogeneity in cervical cancer

Nurses promote hope behind bars in Norwegian prisons

Study reveals trends and future projections of cancer mortality in China

Study highlights growing mental health concerns among U.S. international student population

Mapping the brain's body regulation and sensing system using 7 Tesla MRI

Genomic mapping of resistance mutations in A. baumannii

Radiometer featured in the 2025 edition of the Healthcare & Life Sciences Review Denmark

Comprehensive kinase atlas reveals new insights into cell signaling and disease

Diabetes drug blunts exercise-induced health improvements

Study reveals uneven access to abortion pill mifepristone in British Columbia

New initiative focuses on advancing human disease research through AI and frontier biology

Machine learning advances human-centric drug toxicity prediction

New project aims to reduce addiction through prevention infrastructure development

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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