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Clinical trial confirms ivermectin safety in very young children down to 5 kg

Millions of very young children currently excluded from treatment with the drug ivermectin could be safely included in ongoing campaigns against challenging and often neglected tropical diseases such as intestinal worms, scabies and river blindness, according to results from a clinical trial presented today at the Annual Meeting of the American Society of Tropical Medicine and Hygiene (ASTMH).

10 Nov 2025

Micro-RNA in sperm proves vital for human embryogenesis

The sperm is not a passive supplier of genetic material to the egg. A study from Linköping University, Sweden, shows that certain molecules that come with the sperm, so-called micro-RNA, contribute to the development of the embryo several days after conception. The findings, published in the journal Nature Communications, may in the long term contribute to better diagnosis and treatment of involuntary childlessness.

10 Nov 2025

Cash transfer programs improve health outcomes across low- and middle-income countries

Large-scale, government-led cash transfer programs drove significant improvements in health outcomes across low- and middle-income countries (LMICs), according to a major new study in The Lancet from researchers at the University of Pennsylvania Perelman School of Medicine.

10 Nov 2025

Prasugrel shows advantage over ticagrelor in diabetic patients after stent placement

One year of dual antiplatelet therapy with one of two potent P2Y12 inhibitors-ticagrelor or prasugrel-in people with Type 1 or Type 2 diabetes who had received a drug-eluting stent did not offer the same level of benefit at preventing stent clotting, heart attacks and bleeding complications, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

New initiative boosts cholesterol control in veterans with heart and blood vessel disease

A quality improvement program helped reduce "bad cholesterol" (LDL or low-density lipoprotein) levels among military veterans who have heart and blood vessel disease, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Healthy meal deliveries boost quality of life for people with heart failure

Providing healthy, medically tailored meals or boxes of fresh produce along with nutrition counseling with a dietitian led to improved quality of life for people with heart failure compared to people who received dietary counseling without healthy food deliveries, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

New drug combination gains Fast Track Designation for metastatic colorectal cancer

The U.S. Food and Drug Administration has granted Fast Track Designation to a new drug combination for metastatic colorectal cancer, following encouraging results from a clinical trial led in part by the University of Oklahoma Health Stephenson Cancer Center.

10 Nov 2025

Single daily polypill improves heart function and quality of life in heart failure patients

Adults with heart failure with reduced ejection fraction (HFrEF) who took a "polypill" combining medications prescribed for the treatment of heart failure, had improved heart function and symptoms, better quality of life, fewer hospitalizations and greater medication adherence than those taking the medications individually, according to a late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

MRI-based blood flow testing offers better answers for unexplained chest pain

Chest pain may still be angina even when coronary angiogram testing shows the main heart arteries look clear. Using stress cardiac stress MRI testing to measure blood flow around the heart appears to improve diagnosis and patient quality of life.

10 Nov 2025

UCLA team receives grant to establish new clinical cancer research center for veterans

Dr. Matthew Rettig and his research team have been awarded a Clinical Cancer Research Center grant from the U.S. Department of Veterans Affairs to establish a new clinical cancer research center that will expand access to precision oncology clinical trials and patient care for veterans across the Southwest United States.

10 Nov 2025

GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

In youth newly diagnosed with type 2 diabetes, GLP-1–based therapies, including semaglutide and tirzepatide, achieved similar blood sugar control but significantly greater reductions in body mass index than metformin. These findings highlight the potential of high-potency GLP-1 agents as effective monotherapy options in managing obesity and glycemic control in adolescents.

10 Nov 2025

Listening to slow-tempo music may boost sleep quality for people over 50

Music therapy significantly improves sleep quality in adults aged 50 and above, showing a moderate-to-large effect compared with control conditions. However, high heterogeneity and methodological weaknesses mean the evidence remains of very low certainty and requires confirmation in larger, standardized trials.

10 Nov 2025

Health care costs jump to the fore as candidates jockey to be California governor

California's gubernatorial election is a year away, and the field of primary candidates is still taking shape. But one persistent issue has already emerged as a leading concern: the cost of health care.

10 Nov 2025

Blood protein pattern linked to increased risk of hereditary atherosclerosis

A specific pattern of proteins in the blood may reflect an increased risk of hereditary atherosclerosis. This is shown in a new study from Karolinska Institutet, examining close relatives of people who had suffered a heart attack at a young age.

10 Nov 2025

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

In a large real-world analysis across three U.S. healthcare databases, semaglutide and tirzepatide showed cardiovascular benefits consistent with randomized trials. Semaglutide lowered heart attack and stroke risk versus sitagliptin, while tirzepatide performed comparably to dulaglutide and semaglutide over one year.

10 Nov 2025

Study advances the possibility of age-based pancreatic cancer treatment

While some risk factors for cancer can be mitigated through lifestyle choices such as diet or exercise, aging is not one of them. In the case of pancreatic cancer, it also can limit treatment options if a patient is too frail to be safely treated with surgery or other alternatives.

10 Nov 2025

Babies show stronger brain response to their mothers’ voices

In a new JNeurosci paper, Sarah Jessen and colleagues, from the University of Lübeck, explored how infants track their mothers' voices compared to unfamiliar voices.

10 Nov 2025

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

In a 15-patient, Phase 1 one, first-in-human trial, a one-time, CRISPR-Cas9 gene-editing therapy safely reduced LDL cholesterol and triglycerides in people with difficult-to-treat lipid disorders, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Daily oral medication matches injectable therapies in reducing bad cholesterol

Among people with a previous heart attack or stroke, or who are at high risk for one, a daily oral medication may offer an effective alternative to injections of PCSK9 inhibitors to lower low-density lipoprotein (LDL or "bad" cholesterol), according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Standard care found to be the better choice for older people with irregular heart rhythms

For older people with irregular heart rhythms who are at high risk of stroke and bleeding, standard care (including the use of blood thinners when indicated) was found to be the better choice compared to a promising, catheter-based procedure, according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

10 Nov 2025

Medical News

Clinical trial confirms ivermectin safety in very young children down to 5 kg

Micro-RNA in sperm proves vital for human embryogenesis

Cash transfer programs improve health outcomes across low- and middle-income countries

Prasugrel shows advantage over ticagrelor in diabetic patients after stent placement

New initiative boosts cholesterol control in veterans with heart and blood vessel disease

Healthy meal deliveries boost quality of life for people with heart failure

New drug combination gains Fast Track Designation for metastatic colorectal cancer

Single daily polypill improves heart function and quality of life in heart failure patients

MRI-based blood flow testing offers better answers for unexplained chest pain

UCLA team receives grant to establish new clinical cancer research center for veterans

GLP-1 drugs beat metformin for weight control in teens with type 2 diabetes

Listening to slow-tempo music may boost sleep quality for people over 50

Health care costs jump to the fore as candidates jockey to be California governor

Blood protein pattern linked to increased risk of hereditary atherosclerosis

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

Study advances the possibility of age-based pancreatic cancer treatment

Babies show stronger brain response to their mothers’ voices

One-time CRISPR therapy safely lowers cholesterol and triglycerides in early trial

Daily oral medication matches injectable therapies in reducing bad cholesterol

Standard care found to be the better choice for older people with irregular heart rhythms

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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