Immunology News and Research

Latest Immunology News and Research

RARα receptor plays unexpected role in T cell activation

According to new research in the journal Immunity, T cells have a nuclear receptor doing something very odd - but very important - to help them fight pathogens and destroy cancer cells.

18 Aug 2023

Severe COVID-19 causes long-lasting changes to immune system stem cells

Severe COVID-19 infection triggers changes that affect gene expression in immune system stem cells, causing long-lasting alterations in the body's immune response, according to a new study by Weill Cornell Medicine and Jackson Laboratory investigators.

18 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

Immune cells present in people months before influenza infection, finds study

St. Jude Children's Research Hospital scientists, in collaboration with the Institute of Environmental Science and Research (ESR) Limited, found that immune cells present in people months before influenza (flu) infection could more accurately predict if an individual would develop symptoms than current methods which primarily rely on antibody levels.

18 Aug 2023

Immunotherapy combination extends progression-free survival in patients with melanoma

A research team co-led by UCLA investigators has shown that an immunotherapy drug combination can be an effective second-line therapy for patients with an aggressive and deadly type of melanoma that is resistant to the widely used immunotherapy drugs known as PD-1 inhibitors.

17 Aug 2023

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering, is reporting the first use of the powerful imaging mass cytometry (IMC) to examine the kidneys of patients with lupus (systemic lupus erythematosus), an autoimmune disease that can affect multiple organs and become fatal, and to diagnose lupus nephritis (LN) in those patients.

17 Aug 2023

Oncolytic viruses could be used to 'warm up' cold tumors and improve immunotherapy

Equipping cancer-infecting, or oncolytic, viruses with tumor-inhibiting genetic cargo stimulates the immune system and helps immunotherapy to shrink or completely clear aggressive tumors in mice, according to a new study in the Journal of Experimental Medicine led by University of Pittsburgh and UPMC researchers.

14 Aug 2023

UAB researchers identify cell-surface marker that indicates fate of T cells

Follicular helper T cells, or Tfh cells, have a crucial role in immune defense. Without Tfh cells, B cells cannot form germinal center, or GC, responses during which high-affinity antibodies are generated.

14 Aug 2023

Scientists leverage machine learning and AI to guide vaccine development

From tackling homework challenges to drafting emails, people are discovering a vast array of applications for natural language processing tools like generative artificial intelligence (AI) engines.

11 Aug 2023

Study provides clues to how harmful T cells cause heart disease

Scientists can finally hunt down a harmful kind of human T cell, thanks to new research led by scientists at La Jolla Institute for Immunology (LJI) and the Medical College of Georgia (MCG) at Augusta University.

10 Aug 2023

MaxCyte and Vittoria Biotherapeutics sign strategic platform license to advance next generation cellular therapies

MaxCyte, Inc., a leading, cell-engineering focused company providing enabling platform technologies to advance the discovery, development and commercialization of next-generation cell-based therapeutics and to support innovative, cell-based research, and Vittoria Biotherapeutics (Vittoria), a leading edge, gene-edited cell therapeutics company with novel platform technologies poised to develop a pipeline of highly differentiated cellular therapies for both oncology and immunology indications, today announced the signing of a strategic platform license (SPL) of MaxCyte’s Flow Electroporation® technology and ExPERT™ platform to Vittoria Biotherapeutics.

From MaxCyte, Inc. 10 Aug 2023

C-Path and Sanofi collaborate to advance Type 1 Diabetes research

Critical Path Institute (C-Path) announced today that Sanofi, a global leader in immunology and diabetes care, has joined its Type 1 Diabetes Consortium (T1DC). Sanofi joins T1DC as part of its commitment to push the boundaries of innovation to improve the lives of those with diabetes.

9 Aug 2023

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

In the ongoing search for a cure for Alzheimer's disease, a burgeoning branch of medicine is bringing new hope. Stem cell therapies are already being used to treat various cancers and disorders of the blood and immune system.

9 Aug 2023

Mice lacking TMCO3 gene have shortened bones

Through next-generation sequencing, investigators have identified a mutation in the TMCO3 gene in two sisters with short stature.

9 Aug 2023

Immunotherapy after stem cell transplantation effectively combats certain childhood nerve tumors

Scientists at St. Anna Children's Cancer Research Institute and the Eberhard Karls University of Tübingen have shown that immunotherapy after stem cell transplantation effectively combats certain nerve tumors in children.

9 Aug 2023

Ebola virus forms "viral factories" to replicate inside host cells

New research in the journal Nature Communications gives scientists an important window into how Ebola virus replicates inside host cells.

9 Aug 2023

Researchers develop a scalable method for engineering blood vessels

University of Melbourne researchers have developed a fast, inexpensive and scalable method for engineering blood vessels from natural tissue.

7 Aug 2023

People living with HIV respond well to COVID-19 infection and vaccination

Researchers examine the antibody response to natural infection or COVID-19 vaccination in individuals living with HIV infection.

7 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Children raised in rural areas have better regulated immune systems

Children raised in rural environments who spend a lot of time outdoors with some exposure to animals grow to have better regulated immune systems than children living in urban environments, a new study has found.

3 Aug 2023

Immunology News and Research

Latest Immunology News and Research

RARα receptor plays unexpected role in T cell activation

Severe COVID-19 causes long-lasting changes to immune system stem cells

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Immune cells present in people months before influenza infection, finds study

Immunotherapy combination extends progression-free survival in patients with melanoma

Powerful imaging mass cytometry could revolutionize the diagnosis of lupus nephritis

Oncolytic viruses could be used to 'warm up' cold tumors and improve immunotherapy

UAB researchers identify cell-surface marker that indicates fate of T cells

Scientists leverage machine learning and AI to guide vaccine development

Study provides clues to how harmful T cells cause heart disease

MaxCyte and Vittoria Biotherapeutics sign strategic platform license to advance next generation cellular therapies

C-Path and Sanofi collaborate to advance Type 1 Diabetes research

Stem cell transplants may be a promising therapeutic against Alzheimer's, study shows

Mice lacking TMCO3 gene have shortened bones

Immunotherapy after stem cell transplantation effectively combats certain childhood nerve tumors

Ebola virus forms "viral factories" to replicate inside host cells

Researchers develop a scalable method for engineering blood vessels

People living with HIV respond well to COVID-19 infection and vaccination

Childhood abuse can induce stress that changes neural networks and functions during growth

Children raised in rural areas have better regulated immune systems

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