Gene News and Research

Latest Gene News and Research

New generation of CRISPR shows safer path to treating genetic diseases

A new generation of CRISPR technology developed at UNSW Sydney offers a safer path to treating genetic diseases like Sickle Cell, while also proving beyond doubt that chemical tags on DNA - often thought to be little more than genetic cobwebs - actively silence genes.

17 Aug 2025

Dementia-like protein clumping found in early pancreatic cancer cells

Cancer Research UK-funded scientists have uncovered dementia-like behaviour in pancreas cells at risk of turning into cancer. The findings provide clues that could help in the treatment and prevention of pancreatic cancer, a difficult-to-treat disease linked to 6,900 deaths in the UK every year.

17 Aug 2025

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Respiratory viruses such as influenza and COVID-19 can reactivate dormant breast cancer cells in the lungs, raising the risk of metastasis. The process is driven by IL-6–induced cell changes and immune suppression, with the highest recurrence risk soon after infection.

14 Aug 2025

Cervicovaginal microbiome features predict severe chlamydia infection

A new study has identified markers that may predict whether a chlamydia infection is likely to ascend into the uterus and endometrium.

14 Aug 2025

Engineered telomerase RNA offers temporary boost to telomere length in human stem cells

Much the way the caps on the ends of a shoelace prevent it from fraying, telomeres - regions of repetitive DNA sequences and a protein structure - protect the tips of chromosomes from damage.

14 Aug 2025

Systems biology identifies sentinel biomarkers bridging ankylosing spondylitis and myocardial infarction

Ankylosing spondylitis (AS) is increasingly recognized as an independent risk factor for premature myocardial infarction (MI), yet the molecular bridge linking chronic axial inflammation to acute coronary events remains poorly mapped.

14 Aug 2025

Origin-recognition complex plays a broad role in the regulation of gene expression

Origin-recognition complex, or ORC, plays an unexpectedly broad role in the regulation of human cell gene expression, according to a study in the journal Cell Reports.

14 Aug 2025

Targeting ferroptosis to eliminate therapy-resistant cancer stem cells

Recent advancements in cancer research are shedding light on a novel therapeutic strategy aimed at overcoming the formidable challenge of cancer stem cells (CSCs).

14 Aug 2025

How circadian biology shapes intestinal regeneration and health

The interplay between the circadian clock, intestinal stem cell niche, and epithelial cell fate is shaping our understanding of how gut homeostasis and cellular regeneration are regulated.

14 Aug 2025

Dual epigenetic marks found to regulate cell identity

Shedding light on what determines how cells become what they are meant to be-nerves, bone, muscles, etc.-can also help researchers understand how diseases develop when these biological programs break down.

14 Aug 2025

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Zheng-Yi Chen, DPhil, associate scientist at the Eaton-Peabody Laboratories, and Ines and Fredrick Yeatts Chair in Otolaryngology, at Mass Eye and Ear, is the senior and co-corresponding author of a paper published in the Journal of Clinical Investigation, "Single Dose Genome Editing Therapy Rescues Auditory and Vestibular Functions in Adult Mice with DFNA41 Deafness."

14 Aug 2025

Brain organoids reveal early changes in familial Alzheimer’s disease

Alzheimer's disease (AD) is the most common neurodegenerative disease in older people, affecting up to 1 in 20 individuals aged 65 and above. In addition to environmental and lifestyle factors, genetic mutations can predispose an individual to AD and some rare forms of inherited "familial" AD (fAD) are caused by known genetic mutations, with these affected individuals developing AD with high probability and at relatively young age.

14 Aug 2025

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

The University of California San Diego's Altman Clinical and Translational Research Institute (ACTRI) has received a seven-year, $80 million Clinical and Translational Science Award (CTSA) from the National Center for Advancing Translational Sciences (NCATS), part of the National Institutes of Health.

14 Aug 2025

Rare immune mutation unlocks universal antiviral protection

For a few dozen people in the world, the downside of living with a rare immune condition comes with a surprising superpower-the ability to fight off all viruses.

14 Aug 2025

New drug discovery platform aims to deliver first-in-class therapies

65LAB has awarded US$1.5 million (approx. S$1.9 million) to Professor Enrico Petretto to advance a breakthrough drug discovery platform developed at Duke-NUS Medical School. The project aims to deliver first-in-class antifibrotic therapies for lung and kidney diseases-conditions that currently have no effective treatment.

14 Aug 2025

Disrupting dopamine pathway stops threadworms from burrowing into the skin

Threadworms, which are a type of parasitic nematode, spend a lot of time crawling around on human skin, poking and prodding to find the best place for entry before burrowing in.

13 Aug 2025

New research sheds light on what makes the human brain unique

Research from scientists at University of California San Diego School of Medicine have shed new light on an age-old question: what makes the human brain unique?

13 Aug 2025

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.

13 Aug 2025

Study investigates aging-related mechanisms in idiopathic pulmonary fibrosis using AI approaches

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease characterized by the excessive accumulation of extracellular matrix components, leading to a gradual decline in lung function and, ultimately, respiratory failure.

13 Aug 2025

DIVA celebrates 30th anniversary with three milestone product launches and new website debut

DIVA, a professional medical display manufacturer with 30 years of experience, announces three major product developments that reinforce its commitment to high-performance imaging solutions.

From DIVA Labs 13 Aug 2025

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Gene News and Research

Latest Gene News and Research

New generation of CRISPR shows safer path to treating genetic diseases

Dementia-like protein clumping found in early pancreatic cancer cells

Respiratory viruses awaken dormant breast cancer cells and raise relapse risk

Cervicovaginal microbiome features predict severe chlamydia infection

Engineered telomerase RNA offers temporary boost to telomere length in human stem cells

Systems biology identifies sentinel biomarkers bridging ankylosing spondylitis and myocardial infarction

Origin-recognition complex plays a broad role in the regulation of gene expression

Targeting ferroptosis to eliminate therapy-resistant cancer stem cells

How circadian biology shapes intestinal regeneration and health

Dual epigenetic marks found to regulate cell identity

Gene editing restores hearing and balance in adult mice with DFNA41 deafness

Brain organoids reveal early changes in familial Alzheimer’s disease

UC San Diego's ACTRI wins $80 million Clinical and Translational Science Award

Rare immune mutation unlocks universal antiviral protection

New drug discovery platform aims to deliver first-in-class therapies

Disrupting dopamine pathway stops threadworms from burrowing into the skin

New research sheds light on what makes the human brain unique

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Study investigates aging-related mechanisms in idiopathic pulmonary fibrosis using AI approaches

DIVA celebrates 30th anniversary with three milestone product launches and new website debut

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production