Epigenetics News and Research

Latest Epigenetics News and Research

Experimental agent fails to increase HDL levels, reveals new study

The search continues for an agent that increases high-density lipoprotein (HDL) and reduces arterial plaque, after the experimental apolipoprotein A1 (apoA1) inducer, RVX-208 failed to do so in the ApoA1 Synthesis Stimulation and Intravascular Ultrasound for Coronary Atheroma Regression Evaluation (ASSURE) study.

5 Sep 2013

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, has entered a non-exclusive license agreement with Horizon Discovery for use of Sigma's CompoZr Zinc Finger Nuclease technology.

3 Sep 2013

Cambridge Epigenetix’s pioneering TrueMethyl™ kit proves successful in beta trial

Cambridge Epigenetix Ltd. (CEGX), a leader in epigenetics tools innovation, today published the results of a successful beta trial evaluating their pioneering TrueMethyl™ oxidative bisulfite sequencing (oxBS-Seq) technology.

3 Sep 2013

Researchers discover role played by epigenetic factors in senescence and age-related diseases

One way cells promote tumor suppression is through a process called senescence, an irreversible arrest of proliferation. Senescence is thought to be associated with normal aging, but is also a protective measure by the body against run-away cell replication.

31 Aug 2013

Study provides first genomic characterization of remission in juvenile rheumatoid arthritis patients

More children with juvenile rheumatoid arthritis are experiencing remission of their symptoms, thanks to new biological therapies, but the remission is not well-understood. A new study published today in Arthritis Research & Therapy provides the first genomic characterization of remission in juvenile rheumatoid arthritis patients.

30 Aug 2013

Dieting before getting pregnant not enough to prevent diabetes risks

Bethesda, MD-While there is never a bad time to address one's own obesity, if you're hoping to lose weight before conception for the sake of your child, here's some bad news: Some of the epigenetic damage might have already been done, even if you lose the weight just before conception.

30 Aug 2013

Sigma Life Science releases genome editing tool for screening and exploratory studies

Sigma-Aldrich Corporation today announced that Sigma Life Science, its innovative biological products and services business, released Sigma CRISPRs, an inexpensive mammalian genome editing tool suitable for screening and exploratory studies.

27 Aug 2013

Scientists discover crucial role of nitric oxide in cellular signaling and health

Scientists at the University of Illinois at Chicago College of Pharmacy have discovered a new role for nitric oxide, a gas molecule crucial for cellular signaling and health.

26 Aug 2013

Researchers find new strategy that has potential to change standard of care for DLBCL patients

Patients with an aggressive lymphoma that often relapses and kills within two years experienced a remission of their cancer and stayed disease-free as long as 28 months after taking a commercially-available drug that made chemotherapy more effective.

20 Aug 2013

New type of cancer immunotherapy harnesses body's immune system to attack tumors

By carefully adjusting the function of crucial immune cells, scientists may have developed a completely new type of cancer immunotherapy—harnessing the body's immune system to attack tumors. To accomplish this, they had to thread a needle in immune function, shrinking tumors without triggering unwanted autoimmune responses.

19 Aug 2013

Researchers provide support for potential importance of vitamin D in pregnancy

Researchers at the MRC Lifecourse Epidemiology Unit, University of Southampton, have demonstrated that the degree to which a gene related to vitamin D action is switched on or off, when measured at birth, predicts bone density of the child at four years of age.

16 Aug 2013

Study shows enhancer RNA molecules may open new avenues for gene therapy

A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could affect the expression of genes and, in consequence, possibly also the progression of various diseases.

14 Aug 2013

Study shows how bioactive component in soy foods plays a role against colon cancer

University of Illinois scientists have evidence that lifelong exposure to genistein, a bioactive component in soy foods, protects against colon cancer by repressing a signal that leads to accelerated growth of cells, polyps, and eventually malignant tumors.

6 Aug 2013

Great-grandmother's cigarette habit could be cause of child's asthma

With some 300 million people around the world living with asthma, a study by Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) researchers that was released ahead-of- print found for the first time that maternal smoking can cause the third generation of offspring to suffer from the chronic lung disease.

6 Aug 2013

New finding suggests potential to improve safety, performance of reprogrammed cells

The enormous promise of regenerative medicine is matched by equally enormous challenges. But a new finding by a team of researchers led by Weill Cornell Medical College has the potential to improve both the safety and performance of reprogrammed cells.

2 Aug 2013

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

If you think stress is killing you, you may be right, but what you don't know is that stress might have harmed your health even before you were born. In a new report appearing in the August 2013 issue of The FASEB Journal, Harvard researchers find that epigenetic disruptions, which are associated with chronic disease later in life, are already common at birth.

2 Aug 2013

Researchers secure $16 million NIH grant to investigate impact of HIV/AIDS on women

Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center today announced they received a $16 million grant from the National Institutes of Health to investigate the impact of HIV and AIDS on women.

31 Jul 2013

Epigenetic changes induced by ADO therapy prevent epilepsy progression

Epilepsy is characterized by recurrent seizures that present in many different ways. In some cases epileptic patients exhibit a progressive increase in both frequency and severity of seizures. Epigenetic changes such as DNA methylation have recently been implied as an underlying cause of several neurologic disorders, including epilepsy.

26 Jul 2013

Silk implants placed in brain of animals may help stop progression of epilepsy

Silk has walked straight off the runway and into the lab. According to a new study published in the Journal of Clinical Investigation, silk implants placed in the brain of laboratory animals and designed to release a specific chemical, adenosine, may help stop the progression of epilepsy.

26 Jul 2013

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

PerFluoroAlkyl Substances (PFASs) and precursor compounds have been used in a wide variety of commercial and industrial products over the past six decades. Applications include water and oil repellent coatings, e.g. for textiles, paper products, carpets and food packaging, pharmaceuticals and surfactants in cleaning products and fire-fighting foams.

25 Jul 2013

Epigenetics News and Research

Latest Epigenetics News and Research

Experimental agent fails to increase HDL levels, reveals new study

Sigma Life Science signs license agreement with Horizon Discovery for CompoZr ZFN technology

Cambridge Epigenetix’s pioneering TrueMethyl™ kit proves successful in beta trial

Researchers discover role played by epigenetic factors in senescence and age-related diseases

Study provides first genomic characterization of remission in juvenile rheumatoid arthritis patients

Dieting before getting pregnant not enough to prevent diabetes risks

Sigma Life Science releases genome editing tool for screening and exploratory studies

Scientists discover crucial role of nitric oxide in cellular signaling and health

Researchers find new strategy that has potential to change standard of care for DLBCL patients

New type of cancer immunotherapy harnesses body's immune system to attack tumors

Researchers provide support for potential importance of vitamin D in pregnancy

Study shows enhancer RNA molecules may open new avenues for gene therapy

Study shows how bioactive component in soy foods plays a role against colon cancer

Great-grandmother's cigarette habit could be cause of child's asthma

New finding suggests potential to improve safety, performance of reprogrammed cells

Study reveals epigenetic mechanisms contribute to chronic disease susceptibility prior to birth

Researchers secure $16 million NIH grant to investigate impact of HIV/AIDS on women

Epigenetic changes induced by ADO therapy prevent epilepsy progression

Silk implants placed in brain of animals may help stop progression of epilepsy

Perfluoroalkyl substances are crossing blood brain barrier of polar bears

Genetics & Genomics - Second Edition eBook

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How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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Epigenetics News and Research

Latest Epigenetics News and Research

Genetics & Genomics - Second Edition eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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