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Collaborative project seeks safer therapies for ischemia and reperfusion injury

Southwest Research Institute (SwRI) and Trinity University will improve a prodrug, a compound activated in the body, to mitigate tissue and organ damage associated with heart attacks, strokes and traumatic injuries.

10 Dec 2025

Why the form of vitamin B12 you take may matter more than your intake

This comprehensive review examines vitamin B12 absorption, physiological roles, deficiency states, and dietary sources, with particular attention to differences between natural and synthetic forms. The authors conclude that while all B12 forms raise circulating levels, methylcobalamin may offer advantages in specific clinical contexts, especially where absorption or metabolic conversion is impaired.

10 Dec 2025

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Synaptic plasticity — the brain's ability to modify the connections between neurons to support learning — is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function.

10 Dec 2025

Hidden infections may play a key role in driving long COVID symptoms

For millions suffering from long COVID, their persistent breathlessness, brain fog and fatigue remain a maddening mystery, but a group of leading microbiologists think they may have cracked the case.

10 Dec 2025

Study elucidates novel mitochondrial mechanisms underlying anti-aging and longevity

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health.

10 Dec 2025

Family history of cardiometabolic disease linked to early heart damage in adolescents

A new study among more than 1,500 British adolescents is the first in the world to assess the association between familial cardiometabolic diseases and the offspring's risk of premature heart damage by early adulthood.

10 Dec 2025

Uterine fibroids linked to higher long-term heart disease risk in women

Long-term heart disease risk in women diagnosed with uterine fibroids was more than 80% higher than in women without fibroids, according to new independent research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

10 Dec 2025

Targeting inflammation may reduce depression severity and anhedonia

Naoise Mac Giollabhui, PhD, of the Department of Psychiatry at Mass General Brigham, is the lead author of a paper published in American Journal of Psychiatry, "Effect of anti-inflammatory treatment on depressive symptom severity and anhedonia in depressed individuals with elevated inflammation: Systematic review and meta-analysis of randomized controlled trials." Richard Liu, PhD, of the Department of Psychiatry at Mass General Brigham, is the senior author.

10 Dec 2025

Anxiety and insomnia linked to reduced natural killer cell levels in young women

Natural killer (NK) cells are the bodyguards of our immune system. As a first line of defense, they destroy invading pathogens, foreign bodies, and infected cells in early stages, thereby preventing them from spreading.

10 Dec 2025

Filtered coffee shows a causal link to healthier HbA1c levels

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee preparation methods show no such benefit. This effect appears to be partly mediated by increases in propionate producing gut bacteria, particularly Veillonella.

10 Dec 2025

Early warning for diabetes: AI model identifies prediabetes risk with high accuracy

A Scientific Reports study developed a pattern neural network that integrates total antioxidant status with clinical and metabolic markers to predict prediabetes in Indian adults. The model achieved very high accuracy and highlighted oxidative stress and waist circumference as key predictors, supporting earlier detection before progression to type 2 diabetes.

10 Dec 2025

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Stanford Medicine investigators have unearthed the biological process by which mRNA-based vaccines for COVID-19 can cause heart damage in some young men and adolescents - and they've shown a possible route to reducing its likelihood.

10 Dec 2025

Home-delivered, medically tailored groceries benefit people with diabetes facing food insecurity

A new study in the Journal of Nutrition Education and Behavior (JNEB), published by Elsevier, evaluated a 12-week home-delivered food and education program among adults in Northwest Arkansas.

10 Dec 2025

Study offers a unified biological model to explain the causes of autism

A new University of California San Diego School of Medicine study offers a unified biological model to explain how genetic predispositions and environmental exposures converge to cause autism spectrum disorder (ASD).

10 Dec 2025

Surprising new function of immune cells uncovered: Excess weight loss prevention

Researchers at the University of California San Diego School of Medicine have uncovered a surprising new function for immune cells: preventing excess weight loss.

10 Dec 2025

How the human brain processes spoken language mirrors AI architecture

A new study reveals that the human brain processes spoken language in a sequence that closely mirrors the layered architecture of advanced AI language models.

10 Dec 2025

Study provides new insights into brain signaling during sleep and wakefulness

An international team led by the University of Michigan has introduced new methods that reveal which regions of the brain were active throughout the day with single-cell resolution.

10 Dec 2025

Analysis of Alzheimer's disease and related dementias uncovers disparities in Maryland's rural communities

A new statewide spatial analysis of Alzheimer's disease and related dementias (ADRD) has uncovered significant disparities in Maryland's rural communities, offering a striking example of how healthcare accessibility is shaping health outcomes across the United States.

10 Dec 2025

Contraception and surgical sterilization associated with increased life expectancy

Blocking reproduction increases lifespan in both males and females of many different species, a new international University of Otago – Ōtākou Whakaihu Waka-led study has found.

10 Dec 2025

Triaptosis could be a promising strategy in the fight against cancer

Cancer remains one of the most critical global public health challenges, exerting profound social, economic, and clinical burdens while limiting gains in human life expectancy.

10 Dec 2025

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Medical Research News

Collaborative project seeks safer therapies for ischemia and reperfusion injury

Why the form of vitamin B12 you take may matter more than your intake

Optogenetic tool helps decipher mechanisms of brain dysfunction in Huntington’s disease

Hidden infections may play a key role in driving long COVID symptoms

Study elucidates novel mitochondrial mechanisms underlying anti-aging and longevity

Family history of cardiometabolic disease linked to early heart damage in adolescents

Uterine fibroids linked to higher long-term heart disease risk in women

Targeting inflammation may reduce depression severity and anhedonia

Anxiety and insomnia linked to reduced natural killer cell levels in young women

Filtered coffee shows a causal link to healthier HbA1c levels

Early warning for diabetes: AI model identifies prediabetes risk with high accuracy

Researchers unravel why mRNA-based vaccines for COVID-19 can cause heart damage

Home-delivered, medically tailored groceries benefit people with diabetes facing food insecurity

Study offers a unified biological model to explain the causes of autism

Surprising new function of immune cells uncovered: Excess weight loss prevention

How the human brain processes spoken language mirrors AI architecture

Study provides new insights into brain signaling during sleep and wakefulness

Analysis of Alzheimer's disease and related dementias uncovers disparities in Maryland's rural communities

Contraception and surgical sterilization associated with increased life expectancy

Triaptosis could be a promising strategy in the fight against cancer

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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