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Blocking a ‘gerozyme’ reverses cartilage loss in mice

An injection that blocks the activity of a protein involved in aging reverses naturally occurring cartilage loss in the knee joints of old mice, a Stanford Medicine-led study has found.

28 Nov 2025

How the gut microbiome links obesity to colorectal cancer

The gut microbiome serves as both a biomarker and therapeutic target in diseases like obesity, metabolic syndrome, and colorectal cancer.

28 Nov 2025

Long COVID symptoms change for 15 months after infection

Long COVID shows varied recovery trajectories, with distinct symptom patterns identified in the RECOVER cohort, emphasizing the need for personalized care.

28 Nov 2025

Music therapy speeds anesthesia recovery in colorectal surgery

Integrating music therapy with anesthesia recovery care enhances recovery in colorectal cancer patients, reducing complications and stabilizing vital signs.

28 Nov 2025

Drinking three to four cups of coffee a day may slow cellular aging

New findings reveal that 3-4 cups of coffee daily may enhance telomere length, potentially slowing cellular aging in individuals with severe mental disorders.

28 Nov 2025

Global analysis shows rising burden of ALS and motor neuron diseases

Amyotrophic lateral sclerosis (ALS) and other motor neuron diseases (MNDs) are major global causes of death. However, their global incidence, mortality, and disability-adjusted life years remain largely unknown, despite their importance for disease prevention and resource allocation.

27 Nov 2025

Texture-based analysis of OCT images reveals early retinal changes in diabetes

Diabetic retinopathy (DR) is a leading cause of blindness among working-age adults, affecting more than 130 million people worldwide.

27 Nov 2025

FOLFIRINOX shows promise as a second-line option for advanced biliary tract cancer

Biliary tract cancers, including intrahepatic, perihilar, and extrahepatic cholangiocarcinoma and gallbladder cancer, are among the most aggressive gastrointestinal malignancies.

27 Nov 2025

Study finds major setbacks in blood pressure prevention and management in England

A comprehensive new analysis by researchers at Queen Mary University of London warns that England has lost the substantial gains made in high blood pressure prevention, diagnosis and management during the 2000s.

27 Nov 2025

Study maps early structural damage in schizophrenia spectrum disorders

Researchers at the University of Seville have identified the possible origins of structural damage in the brains of patients with schizophrenia spectrum disorders (SSDs).

27 Nov 2025

Breakthrough immunotherapy approved for treatment of adults with aggressive blood cancer

Adult patients with an aggressive form of leukemia will be able to receive a breakthrough immunotherapy, which was invented by UCL researchers, on the NHS within weeks following approval for use by the National Institute for Health and Care Excellence (NICE).

27 Nov 2025

New AI models detect dementia with high accuracy using EEG signals

Researchers at örebro University have developed two new AI models that can analyze the brain's electrical activity and accurately distinguish between healthy individuals and patients with dementia, including Alzheimer's disease.

27 Nov 2025

New survey highlights essential role of virtual care for long COVID patients

Preliminary results of a national survey conducted by researchers at the Simon Fraser University Faculty of Health Sciences (SFU FHS) has found that Canadians with Long COVID identified virtual healthcare services as essential to their care.

27 Nov 2025

Higher stent complication risks found in patients with diabetes

Patients with diabetes have an increased risk of complications after stent implantation, according to a study from Karolinska Institutet in Sweden published in Diabetes Care.

27 Nov 2025

Polyphenol-rich dietary patterns linked to lower cardiovascular disease risk

People who regularly consume polyphenol-rich foods and drinks, such as tea, coffee, berries, cocoa, nuts, whole grains and olive oil, may have better long-term heart health.

27 Nov 2025

Driving behavior data may help detect early cognitive decline

Using in-vehicle driving data may be a new way to identify people who are at risk of cognitive decline, according to a study published on November 26, 2025, in Neurology, the medical journal of the American Academy of Neurology.

26 Nov 2025

Experimental drug engasertib shows promise for treating inherited bleeding disorder

Hereditary hemorrhagic telangiectasia (HHT) is the second most common inherited bleeding disorder worldwide, affecting 1 in 3,800 persons.

26 Nov 2025

Researchers uncover key mechanism blocking nerve regeneration in diabetes

Nerve damage is one of the most common and burdensome complications of diabetes. Millions of patients worldwide suffer from pain, numbness, and restricted movement, largely because damaged nerve fibres do not regenerate sufficiently.

26 Nov 2025

Missing cancer gene may boost response to immunotherapy

For some patients with the most common type of lung cancer, known as lung adenocarcinoma, there's new hope.

26 Nov 2025

Study shows one in ten young cancer patients develop metastatic recurrence

A new study of adolescents and young adults (AYAs) with seven common cancers reveals that nearly one in ten patients diagnosed with non-metastatic disease later develop metastatic recurrence - a condition associated with significantly worse survival outcomes.

26 Nov 2025